Fibroblast Growth Factor Receptor 3

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Fibroblast Growth Factor Receptor 3
  Conformer 1
(PDB) 		4k33 (A)
  Conformer 2
(PDB) 		4qqj (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 255 1.71   461 - 636   658 - 753
2 21 5.39   637 - 657

Sequence


           ________________________________________________________________________________________________________________________ 
 4k33(A) : LPADPKWELSRARLTLGKPLGEGAFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYS 
         :                                                                                                                          
 4qqj(A) : LPLDPLWEFPRDRLVLGKPLGEg---QVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVILECAAKGNLREFLRARRPg----- 
           ________________________________________________________________________________________________________________________ 

           __________________________________________________635___________________657_____________________________________________ 
 4k33(A) : FDTSeQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKETTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEE 
         :                                                                                                                          
 4qqj(A) : -----PLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDEVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEE 
           __________________________________________________630___________________652_____________________________________________ 

           _______________________________________________________                                                                  
 4k33(A) : LFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVT**                                                                  
         :                                                                                                                          
 4qqj(A) : LFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSE                                                                  
           _______________________________________________________                                                                  

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		79.1
Translation
(A) 		2.7
Closure
(%) 		100.0
Bending Residues
( green ) 		  635 - 637
  657 - 658
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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