Nadp-Dependent Alcohol Dehydrogenase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Nadp-Dependent Alcohol Dehydrogenase
  Conformer 1
(PDB) 		1y9a (C)
  Conformer 2
(PDB) 		2oui (D)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 296 0.25   16 - 39   53 - 195   208 - 215   236 - 357
2 25 0.29   4 - 15   40 - 52
3 21 0.48   196 - 196   216 - 235

Sequence


           _____________15__________________35_______________52____________________________________________________________________ 
 1y9a(C) : MKGLAMLGIGRIGWIEKKIPECGPLDALVRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVGSLVKRLKVGDKVIVPAITPDWGEEESQRGYPMHSGGMLGGWKFSNFKDGVF 
         :                                                                                                                          
 2oui(D) : MKGLAMLGIGRIGWIEKKIPECGPLDALVRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVGSLVKRLKVGDKVIVPAITPDWGEEESQRGYPMHSGGMLGGWKFSNFKDGVF 
           _____________15__________________35_______________52____________________________________________________________________ 

           ________________________________________________________________________195_________________215_________________235_____ 
 1y9a(C) : SEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGAELANIKLGDTVCVIGIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGKGVDKVV 
         :                                                                                                                          
 2oui(D) : SEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGAELANIKLGDTVCVIGIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGKGVDKVV 
           ________________________________________________________________________195_________________215_________________235_____ 

           ________________________________________________________________________________________________________________________ 
 1y9a(C) : IAGG-vHTFAQAVKMIKPGSDIGNVNYLGEGDNIDIPRSEWGVGMGHKHIHGGLTPGGRVRMEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMKNKPADLIKPVVRIHYDDEDTLH 
         :                                                                                                                          
 2oui(D) : IAGGDVHTFAQAVKMIKPGSDIGNVNYLGEGDNIPIPRSEWGVGMGHKHIHGGLTPGGRVRMEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMKNKPADLIKPVVRIHYDDEDTLH 
           ________________________________________________________________________________________________________________________ 

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		4.9
Translation
(A) 		0.1
Closure
(%) 		82.4
Bending Residues
( green ) 		  15 - 21
  35 - 40
  52 - 56
Bending Region Analysis
Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( yellow ) 		3
Rotation Angle
(deg) 		5.6
Translation
(A) 		0.0
Closure
(%) 		40.3
Bending Residues
( green ) 		  195 - 209
  215 - 217
  235 - 238
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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