Orotate Phosphoribosyltransferase 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Orotate Phosphoribosyltransferase 1
  Conformer 1
(PDB) 		2pry (A)
  Conformer 2
(PDB) 		2prz (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 156 1.49   6 - 19   39 - 164   167 - 169   175 - 196
2 52 1.75   20 - 38   165 - 166   170 - 174   197 - 222

Sequence


           ________________19_________________38___________________________________________________________________________________ 
 2pry(A) : IMLEDYQKNFLELAIECQALRFGSFKLKSGRESPYFFNLGLFNTGKLLSNLATAYAIAIIQSDLKFDVIFGPAYKGIPLAAIVCVKLAEIGGSKFQNIQYAFNRKEAgIIVGSALENKRI 
         :                                                                                                                          
 2prz(A) : **LEDYQKNFLELAIECQALRFGSFKLKSGRESPYFFNLGLFNTGKLLSNLATAYAIAIIQSDLKFDVIFGPAYKGIPLAAIVCVKLAEIGGSKFQNIQYAFNRKEAgIIVGSALENKRI 
           ________________19_________________38___________________________________________________________________________________ 

           __________________________________164_____________________________196_____________________________                       
 2pry(A) : LIIDDVMTa---INEAFEIISNAKGQVVGSIIALDRQEVVSTDDKEGLSATQTVSKKYGIPVLSIVSLIHIITYLEGRITAEEKSKIEQYLQTYGASA                       
         :                                                                                                                          
 2prz(A) : LIIDDVMTAGTAINEAFEIISNAKGQVVGSIIALDRQEVVSTDDKEGLSATQTVSKKYGIPVLSIVSLIHIITYLEGRITAEEKSKIEQYLQTYGAS*                       
           __________________________________164_____________________________196_____________________________                       

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		19.9
Translation
(A) 		0.5
Closure
(%) 		99.1
Bending Residues
( green ) 		  19 - 20
  38 - 39
  164 - 175
  196 - 197
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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