DynDom - Protein Domain Motions

Phosphoenolpyruvate-Protein Phosphotransferase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Phosphoenolpyruvate-Protein Phosphotransferase
Conformer 1 (PDB)	2hwg (A)
Conformer 2 (PDB)	1zym (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	121	1.13	23 - 145
2	110	1.38	5 - 22 146 - 240

Sequence

`___________________22___________________________________________________________________________________________________` `2hwg(A) : ISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHI-lLEDEELEQEIIALIKDKH-tADAAAHEVIEGQASALEELDDE` `:` `1zym(A) : SGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDE` `___________________22___________________________________________________________________________________________________` `_____________________145________________________________________________________________________________________________` `2hwg(A) : YLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTS-tSI-aRSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDK-rA` `:` `1zym(A) : YLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRA` `_____________________145________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2hwg(A) : VQEQVASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFdRDALPTEEEQFAAYKAVAEACGSQAVIVRTdIGGDKELPYnFPKEENPFLGWRAIRIAd` `:` `1zym(A) : VQEQVASE*************************************************************************************************************` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2hwg(A) : RREILRDQLRAILRASAFGKLRIfPiISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVvETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDiSHLYQPsPSVLNLIKQVID` `:` `1zym(A) : ********************************************************************************************************************` `________________________________________________________________________________________________________________________` `_______________________________________________________________________________` `2hwg(A) : ASHAEGKWTGcGELAGDERATLLLLGgLDEFSsAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELtLVNKFIEEKT` `:` `1zym(A) : *****************************************************************************` `_______________________________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	63.9
Translation (A)	1.0
Closure (%)	88.0
Bending Residues ( green )	22 - 24 145 - 152
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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