Vitamin D Hydroxylase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Vitamin D Hydroxylase
  Conformer 1
(PDB) 		3a51 (E)
  Conformer 2
(PDB) 		3a4h (A)
  Window Length 15
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 304 0.82   11 - 100   103 - 147   225 - 231   234 - 395
2 81 2.91   101 - 102   148 - 224   232 - 233

Sequence


           ______________________________________________________________________________________________97________________________ 
 3a51(E) : ALTTTGTEQHDLFSGTFWQNPHPAYAALRAEDPVRKLALPDGPVWLLTRYADVREAFVDPRLSKDWRHRLPEDQRADMPATPTPMMILMDPPDHTRLRKLVGRSFTVRRMNELEPRITEI 
         :                                                                                                                          
 3a4h(A) : **TTTGTEQHDLFSGTFWQNPHPAYAALRAEDPVRKLALPDGPVWLLTRYADVREAFVDPRLSKDWRHTLPEDQRADMPATPTPMMILMDPPDHTRLRKLVGRSFTVRRMNELEPRITEI 
           ______________________________________________________________________________________________97________________________ 

           _____________________145____________________________________________________________________________224_________________ 
 3a51(E) : ADGLLAGLPTDGPVDLMREYAFQIPVQVICELLGLPAEDRDDFSAWSSVLVDDSPADDKNAAMGKLHGYLSDLLERKRTEPDDALLSSLLAVSDMDGDRLSQEELVAMAMLLLIAGHETT 
         :                                                                                                                          
 3a4h(A) : ADGLLAGLPTDGPVDLMREYAFQIPVQVICELLGVPAEDRDDFSAWSSVLVDDSPADDKNAAMGKLHGYLSDLLERKRTEPDDALLSSLLAVSDEDGDRLSQEELVAMAMLLLIAGHETT 
           _____________________145____________________________________________________________________________224_________________ 

           ________________________________________________________________________________________________________________________ 
 3a51(E) : VNLIGNGVLALLTHPDQRKLLAEDPSLISSAVEEFLRFDSPVSQAPIRFTAEDVTYSGVTIPAGEMVMLGLAAANRDADWMPEPDRLDITRDASGGVFFGHGIHFCLGAQLARLEGRVAI 
         :                                                                                                                          
 3a4h(A) : VNLIGNGVLALLTHPDQRKLLAEDPSLISSAVEEFLRFDSPVSQAPIRFTAEDVTYSGVTIPAGEMVMLGLAAANRDADWMPEPDRLDITRDASGGVFFGHGIHFCLGAQLARLEGRVAI 
           ________________________________________________________________________________________________________________________ 

           __________________________________________                                                                               
 3a51(E) : GRLFADRPELALAVGLDELVYRRSTLVRGLSRMPVTMGPRS*                                                                               
         :                                                                                                                          
 3a4h(A) : GRLFADRPELALAVGLDELVYRESTLVRGLSRMPVTMGPRSA                                                                               
           __________________________________________                                                                               

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		15.3
Translation
(A) 		-3.2
Closure
(%) 		76.6
Bending Residues
( green ) 		  97 - 113
  145 - 148
  224 - 238
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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