Akap9-Braf Fusion Protein

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Akap9-Braf Fusion Protein
  Conformer 1
(PDB) 		3og7 (A)
  Conformer 2
(PDB) 		4rzv (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 196 0.95   451 - 453   460 - 461   463 - 463   481 - 487   510 - 717
2 24 1.35   454 - 459   462 - 462   464 - 480
3 22 0.79   488 - 509

Sequence


           __453___459__________________480____487___________________509___________________________________________________________ 
 3og7(A) : DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTAPQLAIVTQWCEGSSLYHHLHAS---fEMKKLIDIARQTARGMDYLH 
         :                                                                                                                          
 4rzv(A) : DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTHHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHASETKFEMKKLIDIARQTARGMDYLH 
           __453___459__________________480____487___________________509___________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 3og7(A) : AKSIIHRDLKSNNIFLHEDNTVKIGDFG------gSILWMAPEVIR----nPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKVRSNCPKRMKRLMAECLKKK 
         :                                                                                                                          
 4rzv(A) : AKSIIHRDLKSNNIFLHEDNTVKIGDFGLATVlSGSILWMAPEVIRMQDSNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKVRSNCPKRMKRLMAECLKKK 
           ________________________________________________________________________________________________________________________ 

           _____________________                                                                                                    
 3og7(A) : RDERPSFPRILAEIEELARE*                                                                                                    
         :                                                                                                                          
 4rzv(A) : RDERPSFPRILAEIEELAREL                                                                                                    
           _____________________                                                                                                    

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		11.9
Translation
(A) 		-0.8
Closure
(%) 		64.7
Bending Residues
( green ) 		  453 - 454
  459 - 464
  480 - 481
Bending Region Analysis
Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( yellow ) 		3
Rotation Angle
(deg) 		16.4
Translation
(A) 		-0.2
Closure
(%) 		47.3
Bending Residues
( green ) 		  487 - 488
  509 - 510
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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