Glutamate Receptor 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor 2
  Conformer 1
(PDB) 		4u2r (A)
  Conformer 2
(PDB) 		1fto (A)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 137 0.5   8 - 109   217 - 217   219 - 247   254 - 258
2 114 0.38   110 - 216   218 - 218   248 - 253

Sequence


           ________________________________________________________________________________________________________109_____________ 
 4u2r(A) : NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
         :                                                                                                                          
 1fto(A) : **TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
           ________________________________________________________________________________________________________109_____________ 

           ___________________________________________________________________________________________216__________________________ 
 4u2r(A) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLS 
         :                                                                                                                          
 1fto(A) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLN 
           ___________________________________________________________________________________________216__________________________ 

           __247___253________                                                                                                      
 4u2r(A) : EQGVLDKLKNKWWYDKGEC                                                                                                      
         :                                                                                                                          
 1fto(A) : EQGLLDKLKNKWWYDKGEC                                                                                                      
           __247___253________                                                                                                      

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		2.8
Translation
(A) 		0.2
Closure
(%) 		66.0
Bending Residues
( green ) 		  109 - 110
  216 - 219
  247 - 248
  253 - 258
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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