Triosephosphate Isomerase (E.C.5.3.1.1)

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Triosephosphate Isomerase (E.C.5.3.1.1)
  Conformer 1
(PDB) 		1tpd (A)
  Conformer 2
(PDB) 		5tim (B)
  Window Length 9
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 201 0.32   6 - 127   147 - 163   185 - 246
2 24 0.36   128 - 146   164 - 168

Sequence


           ________________________________________________________________________________________________________________________ 
 1tpd(A) : SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 
         :                                                                                                                          
 5tim(B) : SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVVASTFVHLAMTKERLSHPKFVIAAQNAIAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 
           ________________________________________________________________________________________________________________________ 

           ___127________________146______________163__168_________________________________________________________________________ 
 1tpd(A) : MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 
         :                                                                                                                          
 5tim(B) : MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 
           ___127________________146______________163__168_________________________________________________________________________ 

           _________                                                                                                                
 1tpd(A) : FVDIIKATQ                                                                                                                
         :                                                                                                                          
 5tim(B) : FVDIIKATQ                                                                                                                
           _________                                                                                                                

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		3.4
Translation
(A) 		-0.2
Closure
(%) 		98.1
Bending Residues
( green ) 		  127 - 128
  146 - 147
  163 - 164
  168 - 185
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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