Elongation Factor 1-Alpha

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Elongation Factor 1-Alpha
  Conformer 1
(PDB) 		4c0s (A)
  Conformer 2
(PDB) 		1jny (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 385 2.73   7 - 33   58 - 441
2 23 2.83   34 - 57

Sequence


           ____________________________33______________________57__________________________________________________________________ 
 4c0s(A) : EKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEM-kGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEF 
         :                                                                                                                          
 1jny(A) : *KPHLNLIVIGHVDHGKSTLVGRLLMDRGFIDEKTVKEAEEAAKKLGKESEKFAFLLDRLKEE-----------mRFETKKYFFTIIDAPGHRDFVKNMITGASQADAAILVVSAKKGEY 
           ____________________________32______________________56__________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 4c0s(A) : EAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAY-eKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTI-LPPrPTD 
         :                                                                                                                          
 1jny(A) : EAGMSVEGQTREHIILAKTMGLDQLIVAVNKMDLTEPPYDEKRYKEIVDQVSKFMRSYGFNTNKVRFVPVVAPSGDNITHKSENMKWY------------NGPTLEEYLDQLELPPKPVD 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 4c0s(A) : KPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDC 
         :                                                                                                                          
 1jny(A) : KPLRIPIQDVYSISGVGTVPVGRVESGVLKVGDKIVFMPAGKVGEVRSIETHHTKMDKAEPGDNIGFNVRGVEKKDIKRGDVVGHP-NNPPTVADEFTARIIVVWHPTALANGYTPVLHV 
           ________________________________________________________________________________________________________________________ 

           ____________________________________________________________________________________________                             
 4c0s(A) : HTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSA                             
         :                                                                                                                          
 1jny(A) : HTASVACRVSELVSKLDPRTGQEAEKNPQFLKQGDVAIVKFKPIKPLCVEKYNEFPPLGRFAMRDMGKTVGVGIIVDVKP************                             
           ____________________________________________________________________________________________                             

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		75.0
Translation
(A) 		2.4
Closure
(%) 		67.6
Bending Residues
( green ) 		  33 - 34
  57 - 58
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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