Glutamate Receptor, Ionotropic Kainate 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor, Ionotropic Kainate 2
  Conformer 1
(PDB)
4h8i (B)
  Conformer 2
(PDB)
4mh5 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 142 1.16   5 - 108   215 - 253
2 108 0.82   109 - 214   254 - 256

Sequence


           _________________________________________________________________________________________________________108____________ 
 4h8i(B) : **NRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKGTP 
         :                                                                                                                          
 4mh5(A) : GTNRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDD-KGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKGTP 
           _________________________________________________________________________________________________________109____________ 

           _________________________________________________________________________________________212____________________________ 
 4h8i(B) : IDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQE 
         :                                                                                                                          
 4mh5(A) : IDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSK-PSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQE 
           _________________________________________________________________________________________212____________________________ 

           __________253_____                                                                                                       
 4h8i(B) : EGKLHMMKEKWWRGNGCP                                                                                                       
         :                                                                                                                          
 4mh5(A) : EDKLHIMKEKWWRGSGCP                                                                                                       
           __________253_____                                                                                                       

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
25.7
Translation
(A)
0.2
Closure
(%)
99.8
Bending Residues
( green )
  108 - 110
  212 - 215
  253 - 256
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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