Fab Fragment From Human Immunoglobulin Igg1 (Lambda, Hil)

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Fab Fragment From Human Immunoglobulin Igg1 (Lambda, Hil)
  Conformer 1
(PDB)
8fab (D)
  Conformer 2
(PDB)
8fab (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 120 0.85   3 - 122
2 89 0.73   123 - 219

Sequence


           ______________________________________________________________________________________________________________________12 
 8fab(D) : AVKLVQAGGGVVQPGRSLRLSCIASGFTFSNYGMHWVRQAPGKGLEWVAVIWYNGSRTYYGDSVKGRFTISRDNSKRTLYMQMNSLRTEDTAVYYCARDPDILTAFSFDYWGQGVLVTVS 
         :                                                                                                                          
 8fab(B) : aVKLVQAGGGVVQPGRSLRLSCIASGFTFSNYGMHWVRQAPGKGLEWVAVIWYNGSRTYYGDSVKGRFTISRDNSKRTLYMQMNSLRTEDTAVYYCARDPDILTAFSFDYWGQGVLVTVS 
           ______________________________________________________________________________________________________________________12 

           1_____________________________________________________________________________________________________                   
 8fab(D) : SASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK                   
         :                                                                                                                          
 8fab(B) : SASTKGPSVFPLAP--------tAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK                   
           1_____________________________________________________________________________________________________                   

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
16.4
Translation
(A)
2.1
Closure
(%)
100.0
Bending Residues
( green )
  121 - 124
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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