Lactoferrin

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Lactoferrin
  Conformer 1
(PDB)
1ce2 (A)
  Conformer 2
(PDB)
1jw1 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 347 0.88   140 - 140   325 - 329   332 - 336   345 - 378   383 - 682   686 - 687
2 337 0.96   4 - 139   141 - 324   330 - 331   337 - 344   379 - 382   683 - 685

Sequence


           ________________________________________________________________________________________________________________________ 
 1ce2(A) : APRKNVRWCTISQPEWLKCHRWQWRMKKLGAPSITCVRRASVLECIRAITEKKADAVTLDGGMVFEAGRDPYKLRPVAAEIYGTKESPQTHYYAVAVVKKGSNFQLDQLQGRNSCHTGLG 
         :                                                                                                                          
 1jw1(A) : APRKNVRWCAISLPEWSKCYQWQRRMRKLGAPSITCVRRTSVLECIRAIAGKNADAVTLDDGMVFEAGRDPYKLRPVAAEIYGTEKSPQTHYYAVAVVKKGSNFKLDQLQGQKSCHMGLG 
           ________________________________________________________________________________________________________________________ 

           ________________139_____________________________________________________________________________________________________ 
 1ce2(A) : RSAGWNIPMGILRPYLSWTESLEPLQGAVAKFFSASCVPCVDRQAYPNLCQLCKGEGENQCACSPREPYFGYSGAFKCLQDGAGDVAFVKETTVFENLPEKADRDQYELLCLNNTRAPVD 
         :                                                                                                                          
 1jw1(A) : RSAGWNIPVGILRPPLSWTESAEPLQGAVARFFSASCVPCVDGKAYPNLCQLCKGVGENKCACSSQEPYFGYSGAFKCLQDGAGDVAFVKETTVFENLPEKADRDQYELLCLNNTRAPVD 
           ________________139_____________________________________________________________________________________________________ 

           _________________________________________________________________________________324__329____336_____344________________ 
 1ce2(A) : AFKECHLAQVPSHAVVARSVDGKEDLIWKLLSKAQEKFGKNKSGSFQLFGSPPGQRDLLFKDSALGFLRIPSKVDSALYLGSRYLTALKNLRETAEEVQARRARVVWCAVGPEEQKKCQQ 
         :                                                                                                                          
 1jw1(A) : AFKECHLAQVPSHAVVARSVDGKENLIWELLRKAQEKFGKNKSQRFQLFGSPEGRRDLLFKDSALGFLRIPSKVDSALYLGSRYLTALKNLRETAEEVKARCTRVVWCAVGPEEQSKCQQ 
           _________________________________________________________________________________324__329____336_____344________________ 

           _______________378_382__________________________________________________________________________________________________ 
 1ce2(A) : WSQQSGQIVTCATASTTDDCIALVLKGEADALSLDGGYIYTAGKCGLVPVLAENRKSSKHSSLDCVLRPTEGYLAVAVVKKANEGLTWNSLKGKKSCHTAVDRTAGWNIPMGLIANQTGS 
         :                                                                                                                          
 1jw1(A) : WSEQSGQNVTCATASTTDDCIALVLKGEADALSLDGGYIYTAGKCGLVPVMAENRKSSKHSSLDCVLRPTEGYLAVAVVKKANEGLTWNSLKGKKSCHTAVDRTAGWNIPMGLIANQTGS 
           _______________378_382__________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1ce2(A) : CAFDEFFSQSCAPGADPKSRLCALCAGDDQGLDKCVPNSKEKYYGYTGAFRCLAEDVGDVAFVKNDTVWENTNGESTADWAKNLNREDFRLLCLDGTRKPVTEAQSCHLAVAPNHAVVSL 
         :                                                                                                                          
 1jw1(A) : CAFDEFFSQSCAPGADPKSSLCALCAGDDQGLDKCVPNSKEKYYGYTGAFRCLAEDVGDVAFVKNDTVWENTNGESSADWAKNLNREDFRLLCLDGTTKPVTEAQSCYLAVAPNHAVVSR 
           ________________________________________________________________________________________________________________________ 

           _______________________________________________________________________________682_______                                
 1ce2(A) : SERAAHVEQVLLHQQALFGENGKNCPDKFCLFKSETKNLLFNDNTECLAKLGGRPTYEEYLGTEYVTAIANLKKCSTSPLLEACAFLTR                                
         :                                                                                                                          
 1jw1(A) : SDRAAHVEQVLLHQQALFGKNGKNCPDKFCLFKSETKNLLFNDNTECLAKLGGRPTYEKYLGTEYVTAIANLKKCSTSPLLEACAFLTR                                
           _______________________________________________________________________________682_______                                

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
9.3
Translation
(A)
-0.4
Closure
(%)
99.8
Bending Residues
( green )
  139 - 141
  324 - 327
  329 - 332
  336 - 337
  344 - 345
  378 - 379
  382 - 383
  682 - 686
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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