Glutamate Receptor, Ionotropic Kainate 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor, Ionotropic Kainate 2
  Conformer 1
(PDB) 		1yae (D)
  Conformer 2
(PDB) 		1s50 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 137 0.77   431 - 517   520 - 532   764 - 800
2 112 0.72   518 - 519   533 - 763   801 - 802

Sequence


           ____________________________________________________________________________________________517____________532__________ 
 1yae(D) : NITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILY 
         :                                                                                                                          
 1s50(A) : ******SNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILY 
           _____________________________________________________________________________________________90____________105__________ 

           __________________________________________________________________________________________________763___________________ 
 1yae(D) : RK---iDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAI 
         :                                                                                                                          
 1s50(A) : RKGTPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAI 
           __________________________________________________________________________________________________216___________________ 

           _______________800______                                                                                                 
 1yae(D) : LQLQEEGKLHMMKEKWWRGNGC**                                                                                                 
         :                                                                                                                          
 1s50(A) : LQLQEEGKLHMMKEKWWRGNGCPE                                                                                                 
           _______________253______                                                                                                 

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		13.6
Translation
(A) 		-0.1
Closure
(%) 		90.8
Bending Residues
( green ) 		  517 - 520
  532 - 533
  763 - 764
  800 - 802
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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