Adenylate Cyclase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Adenylate Cyclase
  Conformer 1
(PDB)
1ykd (A)
  Conformer 2
(PDB)
1ykd (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 195 0.6   60 - 109   111 - 111   114 - 261
2 174 0.48   110 - 110   112 - 113   262 - 432

Sequence


           _________________________________________________109____________________________________________________________________ 
 1ykd(A) : VTEVEQKLQIVHQTLSMLDSHGFENILQEMLQSITLKTGELLGADRTTIFLLDEEKQELWSIVAAGEGDRSLEIRIPADKGIAGEVATFKQVVNIPFDFYHDPRSIFAQKQEKITGYRTY 
         :                                                                                                                          
 1ykd(B) : VTEVEQKLQIVHQTLSMLDSHGFENILQEMLQSITLKTGELLGADRTTIFLLDEEKQELWSIVAAG----sLEIRIPADKGIAGEVATFKQVVNIPFDFYHDPRSIFAQKQEKITGYRTY 
           _________________________________________________109____________________________________________________________________ 

           _________________________________________________________________________________261____________________________________ 
 1ykd(A) : TMLALPLLSEQGRLVAVVQLLNKLKPYSPPDALLAERIDNQGFTSADEQLFQEFAPSIRLILESSRSFYIATQKQRAAAAMMKAVKSLSQSSLDLEDTLKRVMDEAKELMNADRSTLWLI 
         :                                                                                                                          
 1ykd(B) : TMLALPLLSEQGRLVAVVQLLNKLKPYSPPDALLAERIDNQGFTSADEQLFQEFAPSIRLILESSRSFYIATQKQRAAAAMMKAVKSLSQSSLDLEDTLKRVMDEAKELMNADRSTLWLI 
           _________________________________________________________________________________261____________________________________ 

           ________________________________________________________________________________________________________________________ 
 1ykd(A) : DRDRHELWTKITQDNGSTKELRVPIGKGFAGIVAASGQKLNIPFDLYDHPDSATAKQIDQQNGYRTCSLLCMPVFNGDQELIGVTQLVNKKKTGEFPPYNPETWPIAPECFQASFDRNDE 
         :                                                                                                                          
 1ykd(B) : DRDRHELWTKITQDNGSTKELRVPIGKGFAGIVAASGQKLNIPFDLYDHPDSATAKQIDQQNGYRTCSLLCMPVFNGDQELIGVTQLVNKKKTGEFPPYNPETWPIAPECFQASFDRNDE 
           ________________________________________________________________________________________________________________________ 

           ________________________                                                                                                 
 1ykd(A) : EFMEAFNIQAGVALQNAQLFATV*                                                                                                 
         :                                                                                                                          
 1ykd(B) : EFMEAFNIQAGVALQNAQLFATVK                                                                                                 
           ________________________                                                                                                 

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
5.9
Translation
(A)
0.4
Closure
(%)
72.9
Bending Residues
( green )
  109 - 114
  261 - 262
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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