6-Deoxyerythronolide B Synthase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name 6-Deoxyerythronolide B Synthase
  Conformer 1
(PDB)
2hg4 (A)
  Conformer 2
(PDB)
2hg4 (D)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 835 0.88   37 - 899
2 26 1.08   11 - 36

Sequence


           ___________________________36___________________________________________________________________________________________ 
 2hg4(A) : *EEKLRRYLKRTVTELDSVTARLREVEHRAGEPIAIVGaCRFPGDVDSPESFWEFVSGGGDAIAEAPADRGWEPDPDARLGGlAAAGDFDAGFFGISPREALAdPQQRIlEISWEALERA 
         :                                                                                                                          
 2hg4(D) : TEEKLRRYLKRTVTELDSVTARLREVEHRAGEPIAIVGaCRFPGDVDSPESFWEFVSGGGDAIAEAPADRGWEPDPDARLGGlAAAGDFDAGFFGISPREALAdPQQRIlEISWEALERA 
           ___________________________36___________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2hg4(A) : GHDPVSLRGSATGVFTGVGTVDYGPRPDEAPDEVLGYVGTGTASSVASGRVAYCLGLEGPAtVDTACSSGLTALHLAeSLRRDECGLALAGGVTVsSPGAFTEFRSQGGLAADGRCKPFS 
         :                                                                                                                          
 2hg4(D) : GHDPVSLRGSATGVFTGVGTVDYGPRPDEAPDEVLGYVGTGTASSVASGRVAYCLGLEGPAtVDTACSSGLTALHLAeSLRRDECGLALAGGVTVsSPGAFTEFRSQGGLAADGRCKPFS 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2hg4(A) : KAADGFGLAEGAGVLVLQRLSAARREGRPVLAVLRGSAVNQDGASNGLTAPSGPAQQRVIRRALENAGVRAGDVDYVEAHGTGTRLGDPIEVHALLSTYGAERDPDDPLWIGSVKSNIGH 
         :                                                                                                                          
 2hg4(D) : KAADGFGLAEGAGVLVLQRLSAARREGRPVLAVLRGSAVNQDGASNGLTAPSGPAQQRVIRRALENAGVRAGDVDYVEAHGTGTRLGDPIEVHALLSTYGAERDPDDPLWIGSVKSNIGH 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2hg4(A) : TQAAAGVAGVkAVLALRHGEpRTLHFDEPSPQIEW--aVSVVSQARSWPAGERPRRAGVSSFGISGTNAHVIVEEAPEADgPVPLVLSGRDEQArAQAGRLADHLAREPRNSLRDTGFTL 
         :                                                                                                                          
 2hg4(D) : TQAAAGVAGVkAVLALRHGEpRTLHFDEPSPQIEWDLaVSVVSQARSWPAGERPRRAGVSSFGISGTNAHVIVEEAPEADgPVPLVLSGRDEQArAQAGRLADHLAREPRNSLRDTGFTL 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2hg4(A) : ATRRSAWEHRAVVVGDRDEALAGLRAVADGRIADRTATGQARTRRGVAvFPGQGAQWQGaRDLLRESQVFADSIRDCERALAPHVDWSLTDLLSGARPLDRVDVVQPALFAVvSLAALWR 
         :                                                                                                                          
 2hg4(D) : ATRRSAWEHRAVVVGDRDEALAGLRAVADGRIADRTATGQARTRRGVAvFPGQ--qWQGaRDLLRESQVFADSIRDCERALAPHVDWSLTDLLSGARPLDRVDVVQPALFAVvSLAALWR 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2hg4(A) : SHGVEPAAVVGHSQGEIAAAHVAGALTLEDAAKLVAVRSRVLRRLGGQGGaSFGLGTEQAAERIGRFAGALSIASVNGPRSVVVAGESGPLDELIAECEAEAHKARRIPVDYASHSPQVE 
         :                                                                                                                          
 2hg4(D) : SHGVEPAAVVGHSQGEIAAAHVAGALTLEDAAKLVAVRSRVLRRLGGQGGaSFGLGTEQAAERIGRFAGALSIASVNGPRSVVVAGESGPLDELIAECEAEAHKARRIPVDYASHSPQVE 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2hg4(A) : SLREELLTELAGISPVSADVALYSTTTGQPIDTATdTAYWYANLREQVRFQDATRQLAEAGFDAFVEVSPHPVLTVGIEATLDSALPADAGACVVGTLRRDRGGLADFHTALGEAYAQGV 
         :                                                                                                                          
 2hg4(D) : SLREELLTELAGISPVSADVALYSTTTGQPIDTATdTAYWYANLREQVRFQDATRQLAEAGFDAFVEVSPHPVLTVGIEATLDSALPADAGACVVGTLRRDRGGLADFHTALGEAYAQGV 
           ________________________________________________________________________________________________________________________ 

           ______________________________                                                                                           
 2hg4(A) : EVDWSPAFADARPVELPVYPFQRQRYWLPI                                                                                           
         :                                                                                                                          
 2hg4(D) : EVDWSPAFADARPVELPVYPFQRQRYWLPI                                                                                           
           ______________________________                                                                                           

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
32.7
Translation
(A)
-1.3
Closure
(%)
93.0
Bending Residues
( green )
  36 - 40
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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