Fibroblast Growth Factor Receptor 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Fibroblast Growth Factor Receptor 2
  Conformer 1
(PDB)
1djs (A)
  Conformer 2
(PDB)
2fdb (P)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 96 3.26   250 - 358
2 93 0.66   153 - 249

Sequence


           ___________________________________________________________________________________________________248__________________ 
 1djs(A) : TLEPEGAPYWTNTEK-eKRLHAVPAANTVKFRCPAGGNP-pT-rWLKNGKEFKQEHRIGGYKVRNQHWSLI-eSVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANA 
         :                                                                                                                          
 2fdb(P) : ****KRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSRHRPILQAGLPANA 
           __________________________________________________________________________________________________2248__________________ 

           ______________________________________________________________________________________                                   
 1djs(A) : STVVGGDVEFVCKVYSDAQPHIQWIKHVEKpYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPA                                   
         :                                                                                                                          
 2fdb(P) : STVVGGDVEFVCKVYSDAQPHIQWIKHV---yLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVL**                                   
           ______________________________________________________________________________________                                   

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
27.1
Translation
(A)
2.8
Closure
(%)
1.7
Bending Residues
( green )
  248 - 250
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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