3-Isopropylmalate Dehydrogenase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name 3-Isopropylmalate Dehydrogenase
  Conformer 1
(PDB)
1cnz (A)
  Conformer 2
(PDB)
1cm7 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 190 0.88   3 - 108   269 - 336   345 - 345   347 - 361
2 169 1.42   109 - 268   337 - 344   346 - 346

Sequence


           _________________________________________________________________________________________________________108____________ 
 1cnz(A) : MSKNYHIAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEGCEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAF 
         :                                                                                                                          
 1cm7(A) : MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAF 
           _________________________________________________________________________________________________________108____________ 

           ________________________________________________________________________________________________________________________ 
 1cnz(A) : CPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESARKRRRKVTSIDKANVLQSSILWREIVNDVAKTYPDVELAHMYIDNATMQLIKDPSQF 
         :                                                                                                                          
 1cm7(A) : CPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQF 
           ________________________________________________________________________________________________________________________ 

           _________________________268_________________________________________________________________336________________________ 
 1cnz(A) : DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDANDAATAIEQAINRALEEGVRTGDLARGAAAVSTDEMGDIIARYVA 
         :                                                                                                                          
 1cm7(A) : DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAACAIERAINRALEEGIRTGDLARGAAAVSTDEMGDIIARYVA 
           _________________________268_________________________________________________________________336________________________ 

           ___                                                                                                                      
 1cnz(A) : EGV                                                                                                                      
         :                                                                                                                          
 1cm7(A) : EGV                                                                                                                      
           ___                                                                                                                      

Morph

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Status: Initialising

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
27.8
Translation
(A)
-0.5
Closure
(%)
88.5
Bending Residues
( green )
  108 - 109
  268 - 269
  336 - 347
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

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