Erythropoietin Receptor

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Erythropoietin Receptor
  Conformer 1
(PDB)
1eer (B)
  Conformer 2
(PDB)
1ern (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 106 1.27   12 - 119   206 - 206
2 97 1.43   120 - 205   207 - 218

Sequence


           _____________________________________________________________________________________________________________119________ 
 1eer(B) : DPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGQYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGL 
         :                                                                                                                          
 1ern(B) : **KFESKAALLAA---eELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGL 
           _____________________________________________________________________________________________________________119________ 

           ___________________________________________________________________________205_________________                          
 1eer(B) : VARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGQGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSEWSEPVSLLT**                          
         :                                                                                                                          
 1ern(B) : VARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAG-gAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPS                          
           ___________________________________________________________________________205_________________                          

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
25.9
Translation
(A)
-0.3
Closure
(%)
92.4
Bending Residues
( green )
  119 - 120
  205 - 207
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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