3C-Like Protease

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name 3C-Like Protease
  Conformer 1
(PDB)
4in1 (A)
  Conformer 2
(PDB)
4inh (A)
  Window Length 11
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 128 0.51   5 - 99   137 - 169
2 29 1.22   100 - 136

Sequence


           _____________________________________________________________________________________________________99_________________ 
 4in1(A) : ***SAPPTLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIAIHQAGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMRIQGRLVHG 
         :                                                                                                                          
 4inh(A) : DDDKAPPTLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIAIHQAGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMRIQGRLVHG 
           _____________________________________________________________________________________________________99_________________ 

           __________135______________________________________________                                                              
 4in1(A) : QSGMLLT--lGTIPGDCGAPYVHKRGNDWVVCGVHAAATKSGNTVVCAVQAGEGEINFE                                                              
         :                                                                                                                          
 4inh(A) : QSGMLLTGdLGTIPGDCGAPYVHKRGNDWVVCGVHAAATKSGNTVVCAVQAG*******                                                              
           __________135______________________________________________                                                              

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
10.6
Translation
(A)
0.4
Closure
(%)
96.0
Bending Residues
( green )
  99 - 100
  135 - 137
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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