Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Basic Fibroblast Growth Factor Receptor 1
  Conformer 1
(PDB) 		3gqi (A)
  Conformer 2
(PDB) 		5am7 (A)
  Window Length 15
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 251 1.49   471 - 639   663 - 757
2 21 5.42   640 - 662

Sequence


           ________________________________________________________________________________________________________________________ 
 3gqi(A) : ******ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 
         :                                                                                                                          
 5am7(A) : AGVSEYELPEDPRWELPRDRLVLGKPLGEg---QVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIMEYASKGNLREYLQARR 
           ________________________________________________________________________________________________________________________ 

           ___________________________________________________________639____________________662___________________________________ 
 3gqi(A) : PPGLEFSFNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHID--kKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLG 
         :                                                                                                                          
 5am7(A) : PPG----------pEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLG 
           ___________________________________________________________639____________________662___________________________________ 

           ________________________________________________________________________                                                 
 3gqi(A) : GSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQElDLS                                                 
         :                                                                                                                          
 5am7(A) : GSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQ*****                                                 
           ________________________________________________________________________                                                 

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		78.1
Translation
(A) 		1.5
Closure
(%) 		99.9
Bending Residues
( green ) 		  639 - 640
  662 - 668
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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