Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Basic Fibroblast Growth Factor Receptor 1
  Conformer 1
(PDB) 		3gqi (A)
  Conformer 2
(PDB) 		6nvh (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 181 2.24   532 - 532   535 - 545   562 - 640   646 - 759
2 85 1.38   467 - 531   533 - 534   546 - 561   641 - 645

Sequence


           _________________________________________________________________531___________545_____________561______________________ 
 3gqi(A) : ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEF 
         :                                                                                                                          
 6nvh(A) : DLPLDPLWEFPRDRLVLGKPLGEg---QVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPG--- 
           _________________________________________________________________520___________534_____________550______________________ 

           ______________________________________________________640_______________________________________________________________ 
 3gqi(A) : SFNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDkKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP 
         :                                                                                                                          
 6nvh(A) : ---SSEGP---LSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLAR-------------lPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIP 
           ______________________________________________________620_______________________________________________________________ 

           ________________________________________________________________                                                         
 3gqi(A) : VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQElDLS                                                         
         :                                                                                                                          
 6nvh(A) : VEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV********                                                         
           ________________________________________________________________                                                         

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		17.5
Translation
(A) 		-0.9
Closure
(%) 		88.1
Bending Residues
( green ) 		  531 - 535
  545 - 546
  561 - 562
  640 - 663
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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