Glutamate Receptor Subunit 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor Subunit 2
  Conformer 1
(PDB) 		1fto (B)
  Conformer 2
(PDB) 		1mqi (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 49 0.58   110 - 111   113 - 119   127 - 131   181 - 187   191 - 214   256 - 259
2 142 0.27   7 - 109   217 - 255
3 62 0.29   112 - 112   120 - 126   132 - 180   188 - 190   215 - 216

Sequence


           ________________________________________________________________________________________________________109_______119___ 
 1fto(B) : **TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
         :                                                                                                                          
 1mqi(A) : NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
           ________________________________________________________________________________________________________109_______119___ 

           _126__131_____________________________________________179___185__190_____________________214____________________________ 
 1fto(B) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLN 
         :                                                                                                                          
 1mqi(A) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLN 
           _126__131_____________________________________________179___185__190_____________________214____________________________ 

           _______252__________                                                                                                     
 1fto(B) : EQGLLDKLKNKWWYDKGEC*                                                                                                     
         :                                                                                                                          
 1mqi(A) : EQGLLDKLKNKWWYDKGECG                                                                                                     
           _______252__________                                                                                                     

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Domain Pairs

Fixed Domain Moving Domain Rotation Angle Translation   (A) Closure Bending Residues  
1 2 10.2 -0.1 65.8   109 - 110   252 - 258 Bending Region Analysis
1 3 6.3 -0.1 83.3   111 - 113   119 - 122   126 - 127   131 - 132   179 - 181   185 - 188   190 - 191   214 - 216 Bending Region Analysis
2 3 16.4 -0.4 92.9   215 - 220 Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 2 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 2

Movement classification:

No Contacts

PyMOL Script

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