Glutamate Receptor 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor 2
  Conformer 1
(PDB) 		4u2r (A)
  Conformer 2
(PDB) 		1fto (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 149 0.42   7 - 110   193 - 193   216 - 259
2 104 0.42   111 - 192   194 - 215

Sequence


           _________________________________________________________________________________________________________110____________ 
 4u2r(A) : NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
         :                                                                                                                          
 1fto(B) : **TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
           _________________________________________________________________________________________________________110____________ 

           ___________________________________________________________________192____________________215___________________________ 
 4u2r(A) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLS 
         :                                                                                                                          
 1fto(B) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLN 
           ___________________________________________________________________192____________________215___________________________ 

           ___________________                                                                                                      
 4u2r(A) : EQGVLDKLKNKWWYDKGEC                                                                                                      
         :                                                                                                                          
 1fto(B) : EQGLLDKLKNKWWYDKGEC                                                                                                      
           ___________________                                                                                                      

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		7.0
Translation
(A) 		-0.2
Closure
(%) 		68.0
Bending Residues
( green ) 		  110 - 111
  192 - 194
  215 - 217
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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