Human Adenosine A2a Receptor/t4 Lysozyme Chimera

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Human Adenosine A2a Receptor/t4 Lysozyme Chimera
  Conformer 1
(PDB) 		3eml (A)
  Conformer 2
(PDB) 		2rh1 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 265 3.43   5 - 206   227 - 302
2 166 1.19   207 - 225

Sequence


           ________________________________________________________________________________________________________________________ 
 3eml(A) : IMGSSVYITVELAIAVLAIL-GNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPF--AITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT 
         :                                                                                                                          
 2rh1(A) : DEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKN 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________206_____________________________________ 
 3eml(A) : RAKGIIAICWVLSFAIGLTPM-LGWNNCGQsQG--CGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKS 
         :                                                                                                                          
 2rh1(A) : KARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETCCDF--FTNQAYAIASSIVS-FYVPLVIMVFVYSRVFQEAKRQLNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKS 
           ________________________________________________________________________________228_____________________________________ 

           ________________________________________________________________________________________________________________________ 
 3eml(A) : PSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTG 
         :                                                                                                                          
 2rh1(A) : PSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTG 
           ________________________________________________________________________________________________________________________ 

           ___222________________________________________________________________________________________                           
 3eml(A) : TWDAYRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ                           
         :                                                                                                                          
 2rh1(A) : TWDAYKFCL-KEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWI--GYVNSGFNPLIYC-RSPDFRIAFQELLCL*****                           
           ___263________________________________________________________________________________________                           

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		83.8
Translation
(A) 		-7.2
Closure
(%) 		15.0
Bending Residues
( green ) 		  206 - 208
  222 - 227
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file Download