DynDom - Protein Domain Motions

Intracellular Protein Transport Protein Uso1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Intracellular Protein Transport Protein Uso1
Conformer 1 (PDB)	6lsu (A)
Conformer 2 (PDB)	6lst (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	356	1.52	17 - 363 409 - 416 676 - 684
2	287	2.79	364 - 408 417 - 675 685 - 716

Sequence

`________________________________________________________________________________________________________________________` `6lsu(A) : QGLIQQPKIQSVDETIPTLCDRVENSTLISDRRSAVLGLKAFSRQYRESVIASGLKPLLNTLKRDYMDEDSVKAILETILILFIRGDGHDDLTRGWISQQSRLQNGKYPSPLVMKeQVDQ` `:` `6lst(A) : *********SVDETIPTLCDRVENSTLISDRRSAVLGLKAFSRQYRESVIASGLKPLLNTLKRDYMDEDSVKAILETILILFIRGDGHDDLTRGWISQQSRLQNGKYPSP-----qVDQ` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6lsu(A) : FSLWIADALTQSEDLIHLLVEFWEIDNFHIRLYTIQLLEAVMATRPLKARSALISLPTSISTMVSLLDDMHEPIRDEAILLLMAVVNDSPHVQKLVAFENIFERLFSIIEEEGGLRGSLV` `:` `6lst(A) : FSLWIADALTQSEDLIHLLVEFWEIDNFHIRLYTIQLLEAVMATRPLKARSALISLPTSISTMVSLLDDMHEPIRDEAILLLMAVVNDSPHVQKLVAFENIFERLFSIIEEEGGLRGSLV` `________________________________________________________________________________________________________________________` `_________________________________________________________________________________________________________________363____` `6lsu(A) : VNDCLSLINNILKYNTSNQTLFLETGNLPKLAHLLSEPISQDEVFFWNDQRIVNINTALDIVSLTVEPGNTVTTKHQNALLDSSVLMVVLRLAFFHNIPKKVRPVALLTAANMVRSNEHA` `:` `6lst(A) : VNDCLSLINNILKYNTSNQTLFLETGNLPKLAHLLSEPISQDEVFFWNDQRIVNINTALDIVSLTVEPGNTVTTKHQNALLDSSVLMVVLRLAFFHNIPKKVRPVALLTAANMVRSNEHA` `_________________________________________________________________________________________________________________363____` `______________________________________408_______________________________________________________________________________` `6lsu(A) : QLEFSKIDVPYFDPSLPVNSTANGGPIKLIPVVSILINWMLYANSVHTFDTRVACSRLLKAYFMDNFDLQRDFLLKQVQLCNNSTNNVGDNfKANLFEVLLNYDAELNLNPFKLFFTTDI` `:` `6lst(A) : QLEFSKIDVPYFDPSLP-------gPIKLIPVVSILINWMLYANSVHTFDTRVACSRLLKAYFMDNFDLQRDFLLKQVQLCNNSTNNV----kANLFEVLLNYDAELNLNPFKLFFTTDI` `______________________________________408_______________________________________________________________________________` `________________________________________________________________________________________________________________________` `6lsu(A) : FMFFFQQDHKYSEELREITRNVTTGNDpLKAIQTISELLTTSLTAADIRIPISYLTFLIYWLFGDFKATNDFLSDKSVIKSLLSFSYQIQDEDVTIKCLVTMLLGVAYEFSSKESPFPRK` `:` `6lst(A) : FMFFFQQDHKYSEELREITRNVTTG--pLKAIQTISELLTTSLTAADIRIPISYLTFLIYWLFGDFKATNDFLSDKSVIKSLLSFSYQIQDEDVTIKCLVTMLLGVAYEFSSKESPFPRK` `________________________________________________________________________________________________________________________` `_____________________________675______684___________________________________` `6lsu(A) : EYFEFITKTLGKDNYASRIKQFKKDSYFSKVDMNEDSILTPELDETGLPKVYFSTYFIQLFNENIYRIRTALSHDP` `:` `6lst(A) : EYFEFITKTLGKDNYASRIKQFKKDSYFSKVDMNEDSILTPELDETGLPKVYFSTYFIQLFNENIYRIRTALSHD` `_____________________________675______684___________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	13.6
Translation (A)	-0.3
Closure (%)	97.1
Bending Residues ( green )	363 - 364 408 - 409 411 - 417 675 - 676 684 - 685
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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