Mitogen-Activated Protein Kinase 14

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Mitogen-Activated Protein Kinase 14
  Conformer 1
(PDB) 		3lfb (A)
  Conformer 2
(PDB) 		3iw5 (A)
  Window Length 13
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 265 0.79   54 - 87   103 - 346
2 55 0.49   10 - 53   88 - 102

Sequence


           ______________________________________________53________________________________87____________102_______________________ 
 3lfb(A) : ERPTFYRQELNKTIWEVPERYQNLSPVGS--sVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKSQKLTDD 
         :                                                                                                                          
 3iw5(A) : ERPTFYRQELNKTIWEVPERYQNLSPVGSyGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKSQKLTDD 
           ______________________________________________53________________________________87____________102_______________________ 

           ________________________________________________________________________________________________________________________ 
 3lfb(A) : HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDSELKILDFG-aTRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARN 
         :                                                                                                                          
 3iw5(A) : HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDSELKILDFGLaTRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARN 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________                         
 3lfb(A) : YIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSLESRDLLIDEWKSLTYDEVISFVPPPL                         
         :                                                                                                                          
 3iw5(A) : YIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSLESRDLLIDEWKSLTYDEVISFVPPPL                         
           ________________________________________________________________________________________________                         

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		5.7
Translation
(A) 		0.3
Closure
(%) 		82.4
Bending Residues
( green ) 		  53 - 54
  87 - 88
  102 - 103
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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