Myosin Heavy Chain

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Myosin Heavy Chain
  Conformer 1
(PDB) 		1b7t (A)
  Conformer 2
(PDB) 		1vom  
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 611 4.98   7 - 492   509 - 707
2 57 2.96   493 - 508   708 - 761

Sequence


           ________________________________________________________________________________________________________________________ 
 1b7t(A) : *****************FSDPDFQYLAVDaFDGKKNCWV---PDEKEGFASAEIQSSKGDEITVKIVADSSTRTVKKDDIQSMNPPKFEKLEDMANMTYLNEASVLYNLRSRYTSGLIYT 
         :                                                                                                                          
 1vom    : NPIHDRTSDYHKYLKVKQGDSDLFKLTVS---DKRYIWYNPDPDERDSYECGEIVSETSDSFTFKTV-DGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRVRYNQDLIYT 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1b7t(A) : YSGLFCIAVNPYRRLPIYTDSVIAKYRGKRKTEIPPHLFSVADNAYQNMVTDRENQSCLITGESGAGKTENTKKVIMYLAKVAC-AeGSLEDQIIQANPVLEAYGNAKTTRNNNSSRFGK 
         :                                                                                                                          
 1vom    : YSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAGRNQgVLEQQILQANPILEAFGNAKTTRNNNSSRFGK 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1b7t(A) : FIRIHFGPTGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQICSNAIPELNDVM-LVTPDSGLYSFINQ-GCLTVDNIDDVEEFKLCDEAFDILGFTKEEKQSMFKCTASILHMGEMKF 
         :                                                                                                                          
 1vom    : FIEIQFNNAGFISGASIQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPES--FNYLNQSGCVDIKGVSDEDEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKF 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1b7t(A) : KqAESDGTAEAEKVAF-----LCGINAGDLLKALLKPKvTKGQ-------NMNQVVNSVGALAKSLYDRMFNWLVRRVNKTLDTKAKRNYYIGVLDIAGFEIFDFNSFEQLCINYTNERL 
         :                                                                                                                          
 1vom    : EKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCSE-RAAYFIGVLDISGFEIFKVNSFEQLCINYTNEKL 
           ________________________________________________________________________________________________________________________ 

           _____492____________507_________________________________________________________________________________________________ 
 1b7t(A) : QQFFNHHMFILEQEEYKKEGIAWEFIDFGMDLQMCIDLIE--KPMGILSILEEECMFPKADDKSFQDKLYQNHMGKNRMFTKPGKPTRPNQGPAHFELHHYAGNVPYSITGWLEKNKDPI 
         :                                                                                                                          
 1vom    : QQFFNHHMFKVEQEEYLKEKINWTFIDFGLDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLH-SHFSK-----KNAKYEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPL 
           _____486____________501_________________________________________________________________________________________________ 

           ____________________________________________________________________________________694_________________________________ 
 1b7t(A) : NENVVALLGASKEPLVAELF-------KAq------TISAVHRESLNKLMKNLYSTHPHFVRCIIPNELKQPGLVDAELVLHQLQCNG--------rKGFPSRLIYSEFKQRYSILAPNA 
         :                                                                                                                          
 1vom    : QQDLELCFKDSSDNVVTKLFNDPNIASRAKKGANFITVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYLLAP-- 
           ____________________________________________________________________________________679_________________________________ 

           ________________________________________________________________________________________________________                 
 1b7t(A) : IPdGKTVSEKILAGLQMDPAEYRLGTTKVFFKAGVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVLRNWQWWKLYSKVKP                 
         :                                                                                                                          
 1vom    : vPRDqKATn-------IDPEQYRFGITKIFFR************************************************************************                 
           ________________________________________________________________________________________________________                 

Morph
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Status: Initialising

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		128.8
Translation
(A) 		1.5
Closure
(%) 		8.3
Bending Residues
( green ) 		  492 - 493
  507 - 509
  694 - 709
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

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