DynDom - Protein Domain Motions

Tarm

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Tarm
Conformer 1 (PDB)	4x7p (B)
Conformer 2 (PDB)	4x7m (B)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	173	0.65	3 - 70 152 - 152 205 - 207 209 - 250 264 - 302 306 - 306 406 - 413 430 - 430 477 - 478 484 - 491
2	134	0.53	71 - 151 153 - 204 208 - 208
3	182	0.46	251 - 263 303 - 305 307 - 405 414 - 429 431 - 476 479 - 483

Sequence

`____________________________________________________________________70__________________________________________________` `4x7p(B) : MKKIFMMVHELDVNKGGMTSSMFNRSKEFYDADIPADIVTFDYKGNYDEIIKALKKQGKMDRRTKMYNVFEYFKQISNNKHFKSNKLLYKHISERLKNTIEIEESKGISRYFDITTGTYI` `:` `4x7m(B) : MKKIFMMVHELDVNKGGMTSSMFNRSKEFYDADIPADIVTFDYKGNYDEIIKALKKQGKMDRRTKMYNVFEYFKQISNNKHFKSNKLLYKHISERLKNTIEIEESKGISRYFDITTRTYI` `____________________________________________________________________70__________________________________________________` `____________________________151__________________________________________________204____________________________________` `4x7p(B) : AYIRKSKSEKVIDFFKDNKRIERFSFIDNKVHMKETFNVDNKVCYQVFYDEKGYPYISRNINANNGAVGKTYVLVNKKEFKNNLALCVYYLEKLIKDSKDSIMICDGPGSFPKMFNTNHK` `:` `4x7m(B) : AYIRKSKSEKVIDFFKDNKRIERFSFIDNKVHMKETFNVDNKVCYQVFYDEKGYPYISRNINANNGAVGKTYVLVNKKEFKNNLALCVYYLEKLIKDSKDSIMICDGPGSFPKMFNTNHK` `____________________________151__________________________________________________204____________________________________` `_______250_____258_________________________________________302__________________________________________________________` `4x7p(B) : NAQKYGVIHVNHHENFDDTGAFKKSEKYIIENANKINGVIVLTEAQRLDILNQFDVENIFTISNFVKIHNAPKHFQTEKIVGHISRMVPTKRIDLLIEVAELVVKKDNAVKFHIYGEGSV` `:` `4x7m(B) : NAQKYGVIHVNHHENFDDTGAFKKSEKYIIENANKINGVIVLTEAQRLDILNQFDVENIFTISNFVKIHNAPKHFQTEKIVGHISRMVPTKRIDLLIEVAELVVKKDNAVKFHIYGEGSV` `_______250_____258_________________________________________302__________________________________________________________` `________________________________________403______412______________429____________________________________________476____` `4x7p(B) : KDKIAKMIEDKNLERNVFLKGYTTTPQKCLEDFKLVVSTSQYEGQGLSMIEAMISKRPVVAFDIKYGPSDFIEDNKNGYLIENHNINDMADKILQLVNNDVLAAEFGSKARENIIEKYST` `:` `4x7m(B) : KDKIAKMIEDKNLERNVFLKGYTTTPQKCLEDFKLVVSTSQYEGQGLSMIEAMISKRPVVAFDIKYGPSDFIEDNKNGYLIENHNINDMADKILQLVNNDVLAAEFGSKARENIIEKYST` `________________________________________403______412______________429____________________________________________476____` `483__________` `4x7p(B) : ESILEKWLNLFNS` `:` `4x7m(B) : ESILEKWLNLFNS` `483__________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	7.2
Translation (A)	-0.2
Closure (%)	80.6
Bending Residues ( green )	70 - 71 151 - 153 204 - 205 207 - 209
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	8.0
Translation (A)	0.5
Closure (%)	88.5
Bending Residues ( green )	250 - 251 258 - 264 302 - 303 305 - 307 403 - 406 412 - 414 429 - 432 476 - 480 483 - 484
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Shear

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