DynDom - Protein Domain Motions

Taste Receptor, Type 1, Member 2A

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Taste Receptor, Type 1, Member 2A
Conformer 1 (PDB)	5x2m (A)
Conformer 2 (PDB)	5x2m (C)
Window Length	7
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	391	0.32	28 - 235 256 - 276 282 - 282 285 - 306 310 - 462
2	22	0.31	244 - 255 277 - 281 283 - 284 307 - 309

Sequence

`________________________________________________________________________________________________________________________` `5x2m(A) : TSEFHLRGDYLIGGLFNIHYVAAANFQRPQAIDCSSKLFILPNYRRFQMMRFSVEEINNSSSLLPNVSLGYQMFDHCSDIHSFPGIFKLLSVNDLIRPWEDlPNAIGVVGPFTSTHALSI` `:` `5x2m(C) : TSEFHLRGDYLIGGLFNIHYVAAANFQRPQAIDCSSKLFILPNYRRFQMMRFSVEEINNSSSLLPNVSLGYQMFDHCSDIHSFPGIFKLLSVNDLIRPWED-pNAIGVVGPFTSTHALSI` `________________________________________________________________________________________________________________________` `____________________________________________________________________________________235_________________255_____________` `5x2m(A) : APIFMTNLFPMVSYGCSGSVFSKENLYPSFLRTVHSNKDVINAIVGIILNFNWRWVAFLYSDDDFGKDGLEQFKNKIEDSEICLAFYKAINVNTDYLQVFKQIEEQNIKVIVVFAPKVYA` `:` `5x2m(C) : APIFMTNLFPMVSYGCSGSVFSKENLYPSFLRTVHSNKDVINAIVGIILNFNWRWVAFLYSDDDFGKDGLEQFKNKIEDSEICLAFYKAINVNTDYLQVFKQIEEQNIKVIVVFAPKVYA` `____________________________________________________________________________________235_________________255_____________` `_____276__281______________________306__________________________________________________________________________________` `5x2m(A) : EAVVESAVQLNVTNKVWIADDGWSLNKKLPSMNGIQNIGTVLGVAQPVVTIPGFTDFIYSAISQmFCNQKCNCSNLSVKSLLNADPSFSFPVYAAVYAIAHALHNTLRCGSDRCPKNITV` `:` `5x2m(C) : EAVVESAVQLNVTNKVWIADDGWSLNKKLPSMNGIQNIGTVLGVAQPVVTIPGFTDFIYSAISQmFCNQKCNCSNLSVKSLLNADPSFSFPVYAAVYAIAHALHNTLRCGSDRCPKNITV` `_____276__281______________________306__________________________________________________________________________________` `_____________________________________________________________________` `5x2m(A) : HPHMILEELKKSNFTLLNQTVQFDENGDPKFGSLSVVFWNSSGNAEEVGSYHFQSSIHLSINKTKIKWF` `:` `5x2m(C) : HPHMILEELKKSNFTLLNQTVQFDENGDPKFGSLSVVFWNSSGNAEEVGSYHFQSSIHLSINKTKIKW*` `_____________________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	3.3
Translation (A)	0.1
Closure (%)	76.8
Bending Residues ( green )	235 - 244 255 - 258 276 - 277 281 - 285 306 - 307 309 - 310
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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