DynDom - Protein Domain Motions

T-Complex Protein 1 Subunit Eta

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	T-Complex Protein 1 Subunit Eta
Conformer 1 (PDB)	6ks6 (H)
Conformer 2 (PDB)	5gw5 (H)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	199	2.14	45 - 48 161 - 183 188 - 188 194 - 200 202 - 247 278 - 382 388 - 390 394 - 401 403 - 404
2	274	2.08	13 - 44 49 - 160 184 - 187 189 - 193 201 - 201 383 - 387 391 - 393 402 - 402 409 - 525
3	22	1.52	256 - 277

Sequence

`_________________________________________44__48_________________________________________________________________________` `6ks6(H) : NFGSQTPTIVVLKEGTDASQGKGQIISNINACVAVQEALKPTLGPLGSDILIVTSNQKTTISNDGATILKLLDVVHPAAKTLVDISRAQDAEVGDGTTSVTILAGELMKEAKPFLEEGIS` `:` `5gw5(H) : *******IVVLKEGTDASQGKGQIISNINACVAVQEALKPTLGPLGSDILIVTSNQKTTISNDGATILKLLDVVHPAAKTLVDISRAQDAEVGDGTTSVTILAGELMKEAKPFLEEGIS` `_________________________________________44__48_________________________________________________________________________` `____________________________________160____________________183_187___193____200_________________________________________` `6ks6(H) : SHLIMKGYRKAVSLAVEKINELAVDITSEK------lERCARTAMSSKLIHNNADFFVKMCVDAVLSLDRNDLDDKLIGIKKIPGGAMEESLFINGVAFKKTFSYAGFEQQPKKFNNPKI` `:` `5gw5(H) : SHLIMKGYRKAVSLAVEKINELAVDITSEKSSGRELLERCARTAMSSKLIHNNADFFVKMCVDAVLSLDRNDLDDKLIGIKKIPGGAMEESLFINGVAFKKTFSYAGFEQQPKKFNNPKI` `____________________________________160____________________183_187___193____200_________________________________________` `___247___________________________277____________________________________________________________________________________` `6ks6(H) : LSLNVELELKAEKDNAEVRVEHVEDYQAIVDAEWQLIFEKLRQVEETGANIVLSKLPIGDLATQFFADRNIFCAGRVSADDMNRVIQAVGGSIQSTTSDIKPEHLGTCALFEEMQIGSER` `:` `5gw5(H) : LSLNVELELKAEKDNAEVRVEHVEDYQAIVDAEWQLIFEKLRQVEETGANIVLSKLPIGDLATQFFADRNIFCAGRVSADDMNRVIQAVGGSIQSTTSDIKPEHLGTCALFEEMQIGSER` `___247___________________________277____________________________________________________________________________________` `__________________382__387___393_____401________________________________________________________________________________` `6ks6(H) : YNLFQGCPQAKTCTLLLRGGAEQVIAEVERSLHDAIMIVKRALQNKLIVAGGGATEMEVSKCLRDYSKTIAGKQQMIINAFAKALEVIPRQLCENAGFDAIEILNKLRLAHSKGEKWYGV` `:` `5gw5(H) : YNLFQGCPQAKTCTLLLRGGAEQVIAEVERSLHDAIMIVKRALQNKLIVAGGGATEMEVSKCLRDYSKTIAGKQQMIINAFAKALEVIPRQLCENAGFDAIEILNKLRLAHSKGEKWYGV` `__________________382__387___393_____401________________________________________________________________________________` `_______________________________________________` `6ks6(H) : VFETENIGDNFAKFVWEPALVKINALNSATEATNLILSVDETITNK` `:` `5gw5(H) : VFETENIGDNFAKFVWEPALVKINALNSATEATNLILSVDETITNKG` `_______________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	19.7
Translation (A)	-1.4
Closure (%)	10.4
Bending Residues ( green )	44 - 45 48 - 49 160 - 161 183 - 184 187 - 189 193 - 198 200 - 202 382 - 383 387 - 388 390 - 391 393 - 394 401 - 409
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	23.0
Translation (A)	1.1
Closure (%)	99.9
Bending Residues ( green )	247 - 257 277 - 278
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Hinge

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