Troponin C

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Troponin C
  Conformer 1
(PDB)
4tnc (A)
  Conformer 2
(PDB)
2tn4 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 123 2.23   6 - 38   67 - 156
2 28 1.34   39 - 66

Sequence


           __________________________________38__________________________66________________________________________________________ 
 4tnc(A) : AMDQQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELADCFRIFDKNADGFIDIEELGEIL 
         :                                                                                                                          
 2tn4(A) : *TDQQAEARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIF 
           __________________________________35__________________________63________________________________________________________ 

           ________________________________________                                                                                 
 4tnc(A) : RATGEHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMMEGVQ                                                                                 
         :                                                                                                                          
 2tn4(A) : RASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMM****                                                                                 
           ________________________________________                                                                                 

Morph

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Status: Initialising

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
48.3
Translation
(A)
1.7
Closure
(%)
98.4
Bending Residues
( green )
  38 - 41
  66 - 73
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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