DynDom - Protein Domain Motions

Wd Repeat-Containing Protein 48

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Wd Repeat-Containing Protein 48
Conformer 1 (PDB)	5k1a (H)
Conformer 2 (PDB)	5k1a (F)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	349	0.46	21 - 22 24 - 359 362 - 366 373 - 375 392 - 398 406 - 409 423 - 426 443 - 444 447 - 451
2	237	0.59	18 - 20 23 - 23 360 - 361 367 - 372 376 - 391 399 - 405 410 - 422 427 - 442 445 - 446 452 - 671

Sequence

`______20________________________________________________________________________________________________________________` `5k1a(H) : RKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELV` `:` `5k1a(F) : KVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELV` `______20________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `5k1a(H) : ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHD` `:` `5k1a(F) : ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHD` `________________________________________________________________________________________________________________________` `______________________________________________________________________________________359____366___372________________39` `5k1a(H) : EGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGtPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVL` `:` `5k1a(F) : EGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKG-pLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVL` `______________________________________________________________________________________359____366___372________________39` `1__396______405_409__________422_426_____________442_____450____________________________________________________________` `5k1a(H) : KACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVNPMvQKGNGYFQVPPHTPVIFGEAGGRTLFR` `:` `5k1a(F) : KACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVNPMvQKGNGYFQVPPHTPVIFGEAGGRTLFR` `1__396______405_409__________422_426_____________442_____450____________________________________________________________` `________________________________________________________________________________________________________________________` `5k1a(H) : LLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHA--kKDRLSASDMLQVRKVMEHVYEKI----dIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYR` `:` `5k1a(F) : LLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHAtLKKDRLSASDMLQVRKVMEHVYEKIINLeDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYR` `________________________________________________________________________________________________________________________` `__` `5k1a(H) : *` `:` `5k1a(F) : QK` `__`

Morph

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Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	5.7
Translation (A)	0.1
Closure (%)	61.7
Bending Residues ( green )	20 - 26 359 - 363 366 - 367 372 - 373 375 - 376 391 - 393 396 - 399 405 - 406 409 - 410 422 - 423 426 - 427 442 - 447 450 - 459
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

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