DynDom - Protein Domain Motions

Uncharacterized Protein

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Uncharacterized Protein
Conformer 1 (PDB)	4x7p (A)
Conformer 2 (PDB)	4x6l (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	102	0.35	4 - 6 27 - 39 211 - 235 240 - 250 262 - 303 430 - 430 485 - 491
2	196	0.39	3 - 3 7 - 26 40 - 210 236 - 239
3	191	0.44	251 - 261 304 - 429 431 - 484

Sequence

`__3__6__________________26___________39_________________________________________________________________________________` `4x7p(A) : MKKIFMMVHELDVNKGGMTSSMFNRSKEFYDADIPADIVTFDYKGNYDEIIKALKKQGKMDRRTKMYNVFEYFKQISNNKHFKSNKLLYKHISERLKNTIEIEESKGISRYFDITTGTYI` `:` `4x6l(A) : MKKIFMMVHELDVNKGGMTSSMFNRSKEFYDADIPADIVTFDYKGNYDEIIKALKKQGKMDRRTKMYNVFEYFKQISNNKHFKSNKLLYKHISERLKNTIEIEESKGISRYFDITTGTYI` `__3__6__________________26___________39_________________________________________________________________________________` `_______________________________________________________________________________________210______________________235_239_` `4x7p(A) : AYIRKSKSEKVIDFFKDNKRIERFSFIDNKVHMKETFNVDNKVCYQVFYDEKGYPYISRNINANNGAVGKTYVLVNKKEFKNNLALCVYYLEKLIKDSKDSIMICDGPGSFPKMFNTNHK` `:` `4x6l(A) : AYIRKSKSEKVIDFFKDNKRIERFSFIDNKVHMKETFNVDNKVCYQVFYDEKGYPYISRNINANNGAVGKTYVLVNKKEFKNNLALCVYYLEKLIKDSKDSIMICDGPGSFPKMFNTNHK` `_______________________________________________________________________________________210______________________235_239_` `_______250________261______________________________________302__________________________________________________________` `4x7p(A) : NAQKYGVIHVNHHENFDDTGAFKKSEKYIIENANKINGVIVLTEAQRLDILNQFDVENIFTISNFVKIHNAPKHFQTEKIVGHISRMVPTKRIDLLIEVAELVVKKDNAVKFHIYGEGSV` `:` `4x6l(A) : NAQKYGVIHVNHHENFDDTGAFKKSEKYIIENANKINGVIVLTEAQRLDILNQFDVENIFTISNFVKIHNAPKHFQTEKIVGHISRMVPTKRIDLLIEVAELVVKKDNAVKFHIYGEGSV` `_______250________261______________________________________302__________________________________________________________` `__________________________________________________________________429___________________________________________________` `4x7p(A) : KDKIAKMIEDKNLERNVFLKGYTTTPQKCLEDFKLVVSTSQYEGQGLSMIEAMISKRPVVAFDIKYGPSDFIEDNKNGYLIENHNINDMADKILQLVNNDVLAAEFGSKARENIIEKYST` `:` `4x6l(A) : KDKIAKMIEDKNLERNVFLKGYTTTPQKCLEDFKLVVSTSQYEGQGLSMIEAMISKRPVVAFDIKYGPSDFIEDNKNGYLIENHNINDMADKILQLVNNDVLAAEFGSKARENIIEKYST` `__________________________________________________________________429___________________________________________________` `483__________` `4x7p(A) : ESILEKWLNLFNS` `:` `4x6l(A) : ESILEKWLNLFNS` `483__________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	3.6
Translation (A)	0.2
Closure (%)	97.5
Bending Residues ( green )	3 - 4 6 - 7 26 - 27 39 - 40 210 - 211 235 - 236 239 - 240
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	6.7
Translation (A)	0.1
Closure (%)	81.1
Bending Residues ( green )	250 - 251 261 - 264 302 - 304 429 - 431 483 - 491
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Shear

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