Translation Initiation Factor If2/eif5b

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Translation Initiation Factor If2/eif5b
  Conformer 1
(PDB) 		1g7r (A)
  Conformer 2
(PDB) 		1g7t (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 110 0.54   346 - 458
2 310 1.37   4 - 345
3 114 0.52   459 - 583

Sequence


           ________________________________________________________________________________________________________________________ 
 1g7r(A) : *KIRSPIVSVLG------tTLLDHIRGSAVAS---qHIGATEIP-dVIEGICGDFLKKFSIRETLPGLFFIDTPG--aFTTLRKRGGALADLAILIVDINEGFKPQTQEALNILR-yRTP 
         :                                                                                                                          
 1g7t(A) : MKIRSPIVSVLGHVDHGKTTLLDHIRGSAVASRiTQHIGATEIPMDVIEGICGDFLKKFSIRETLPGLFFIDTPGHEAFTTLRKRGGALADLAILIVDINEGFKPQTQEALNILRMYRTP 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1g7r(A) : FVVAANKIDRIHGWRVHEGRPF-eTFSKQDIQVQQKLDTKVYELVGKLHEEGFESERFDRVTDFASQVSIIPISAITGEGIPELLTl--gLAQQYLREQLKIEEDSPARGTILEVKEETG 
         :                                                                                                                          
 1g7t(A) : FVVAANKIDRIHGWRVHEGRPFMETFSKQDIQVQQKLDTKVYELVGKLHEEGFESERFDRVTDFASQVSIIPISAITGEGIPELLTMLMGLAQQYLREQLKIEEDSPARGTILEVKEETG 
           ________________________________________________________________________________________________________________________ 

           ____________________________________________________________________________________________345_________________________ 
 1g7r(A) : LG-tIDAVIYDGILRKDDTIA--tSKDVISTRIRSLLKPRPL--kFQKVDEVVAAAGIKIVAPGIDDV-aGSPLRVVTDPEKVREEILSEIEDIKIDTDEAGVVVKADTLGSLEAVVKIL 
         :                                                                                                                          
 1g7t(A) : LGMTIDAVIYDGILRKDDTIAMMTSKDVISTRIRSLLKPRPsRKKFQKVDEVVAAAGIKIVAPGIDDVMAGSPLRVVTDPEKVREEILSEIEDIKIDTDEAGVVVKADTLGSLEAVVKIL 
           ____________________________________________________________________________________________345_________________________ 

           _______________________________________________________________________________452______________________________________ 
 1g7r(A) : RD-yVPIKVADIGDVSRRDVVNAGIALQEDRVYGAIIAFNVKVIPSAAQELKNSDIKLFQGNVIYRL-eEYEEWVRGIEEEKKKKW-eAIIKPASIRLIPKLVFRQSKPAIGGVEVLTGV 
         :                                                                                                                          
 1g7t(A) : RDMYVPIKVADIGDVSRRDVVNAGIALQEDRVYGAIIAFNVKVIPSAAQELKNSDIKLFQGNVIYRLMEEYEEWVRGIEEEKKKKWMEAIIKPASIRLIPKLVFRQSKPAIGGVEVLTGV 
           _______________________________________________________________________________452______________________________________ 

           _____________________________________________________________________________________________                            
 1g7r(A) : IRQGYPL-nDDGETVGTVES-qDKGENLKSASRGQKVA-aIKDAVYGKTIHEGDTLYVDIPENHYHILKEQLlTDEELDL-dKIAEIKRKKN*                            
         :                                                                                                                          
 1g7t(A) : IRQGYPLMNDDGETVGTVESMQDKGENLKSASRGQKVAMAIKDAVYGKTIHEGDTLYVDIPENHYHIL----lTDEELDLMDKIAEIKRKKNP                            
           _____________________________________________________________________________________________                            

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		11.7
Translation
(A) 		-0.1
Closure
(%) 		11.0
Bending Residues
( green ) 		  345 - 346
Bending Region Analysis
Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( yellow ) 		3
Rotation Angle
(deg) 		11.9
Translation
(A) 		-0.4
Closure
(%) 		59.4
Bending Residues
( green ) 		  452 - 459
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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