DNA Polymerase Kappa

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name DNA Polymerase Kappa
  Conformer 1
(PDB) 		6cst (B)
  Conformer 2
(PDB) 		1t94 (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 275 1.73   77 - 408
2 102 1.55   409 - 515

Sequence


           ________________________________________________________________________________________________________________________ 
 6cst(B) : GLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTS 
         :                                                                                                                          
 1t94(B) : *******************************************************TSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTS 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 6cst(B) : NYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIK-nSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAP 
         :                                                                                                                          
 1t94(B) : NYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKqNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAP 
           ________________________________________________________________________________________________________________________ 

           _______________________________________________________________________________________405______________________________ 
 6cst(B) : NTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQYSLC 
         :                                                                                                                          
 1t94(B) : NTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTR---rKSMSVERTFSEINKAEEQYSLC 
           _______________________________________________________________________________________405______________________________ 

           ___________________________________________________________________________________                                      
 6cst(B) : QELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPN                                      
         :                                                                                                                          
 1t94(B) : QELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRAST--sVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFP*                                      
           ___________________________________________________________________________________                                      

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		141.0
Translation
(A) 		1.8
Closure
(%) 		56.4
Bending Residues
( green ) 		  405 - 414
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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