Gamma-Aminobutyric Acid Receptor Subunit Beta-3

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Gamma-Aminobutyric Acid Receptor Subunit Beta-3
  Conformer 1
(PDB) 		6hup (B)
  Conformer 2
(PDB) 		6hug (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 188 0.66   10 - 138   147 - 176   188 - 216
2 144 0.87   139 - 146   177 - 187   217 - 445

Sequence


           ________________________________________________________________________________________________________________________ 
 6hup(B) : NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 
         :                                                                                                                          
 6hug(B) : NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 
           ________________________________________________________________________________________________________________________ 

           _______137______146___________________________176________187__________________________216_______________________________ 
 6hup(B) : LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDAS 
         :                                                                                                                          
 6hug(B) : LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDAS 
           _______137______146___________________________176________187__________________________216_______________________________ 

           ________________________________________________________________________________________________                         
 6hup(B) : AARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRtDVNAIDRWSRIVFPFTFSLFNLVYWLYYV                         
         :                                                                                                                          
 6hug(B) : AARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRtDVNAIDRWSRIVFPFTFSLFNLVYWLYYV                         
           ________________________________________________________________________________________________                         

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		10.9
Translation
(A) 		-0.1
Closure
(%) 		9.9
Bending Residues
( green ) 		  137 - 144
  146 - 147
  176 - 177
  187 - 188
  216 - 217
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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