Gdp-Mannose-Dependent Alpha-(1-2)-Phosphatidylinositol Mannosyltransferase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Gdp-Mannose-Dependent Alpha-(1-2)-Phosphatidylinositol Mannosyltransferase
  Conformer 1
(PDB) 		4nc9 (A)
  Conformer 2
(PDB) 		2gek (A)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 314 2.58   4 - 116   145 - 147   161 - 370
2 41 9.72   117 - 144   148 - 160

Sequence


           ___________________________________________________________________________________________________________116__________ 
 4nc9(A) : GAMRIGMVCPYSFDVPGGVQSHVLQLAEVLRDAGHEVSVLAPASPHVKLPDYVVSGGKAVaRLRFGPATHRKVKKWIAEGDFDVLHIHEPNAPSLSMLALQAAEGPIVATFHTSTTKSLT 
         :                                                                                                                          
 2gek(A) : **MRIGMVCPYSFDVPGGVQSHVLQLAEVLRDAGHEVSVLAPASPHVKLPDYVVSGGKAV----fGPATHRKVKKWIAEGDFDVLHIHEPNAPSLSMLALQAAEGPIVATFHTSTTKSLT 
           ___________________________________________________________________________________________________________116__________ 

           _______________144_____________160______________________________________________________________________________________ 
 4nc9(A) : LSVFQGILRPYHEKIIGRIAVSDLARRWQMEALGSDAVEIPNGVDVASFADAPLLDGYPREGRTVLFLGRYDEPRKGMAVLLAALPKLVARFPDVEILIVGRGDEDELREQAGDLAGHLR 
         :                                                                                                                          
 2gek(A) : LSVFQGILRPYHEKIIGRIAVSDLARRWQMEALGSDAVEIPNGVDVASFADAPLLDGYPREGRTVLFLGRYDEPRKGMAVLLAALPKLVARFPDVEILIVGRGDEDELREQAGDLAGHLR 
           _______________144_____________160______________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 4nc9(A) : FLGQVDDATKASAMRSADVYCAPHLGGESFGIVLVEAMAAGTAVVASDLDAFRRVLADGDAGRLVPVDDADGMAAALIGILEDDQLRAGYVARASERVHRYDWSVVSAQIMRVYETVSGA 
         :                                                                                                                          
 2gek(A) : FLGQVDDATKASAMRSADVYCAPHLGGESFGIVLVEAMAAGTAVVASDLDAFRRVLADGDAGRLVPVDDADGMAAALIGILEDDQLRAGYVARASERVHRYDWSVVSAQIMRVYETVSGA 
           ________________________________________________________________________________________________________________________ 

           _________                                                                                                                
 4nc9(A) : GIKVQVSGA                                                                                                                
         :                                                                                                                          
 2gek(A) : GIKVQVS**                                                                                                                
           _________                                                                                                                

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		156.8
Translation
(A) 		-3.0
Closure
(%) 		37.2
Bending Residues
( green ) 		  116 - 117
  144 - 148
  160 - 163
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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