Human Complement Factor H

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Human Complement Factor H
  Conformer 1
(PDB) 		2uwn (A)
  Conformer 2
(PDB) 		2w80 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 64 0.71   323 - 386
2 55 0.85   387 - 441

Sequence


           ________________________________________________________________386_____________________________________________________ 
 2uwn(A) : MGLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWSPT 
         :                                                                                                                          
 2w80(A) : *TLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWSPT 
           ________________________________________________________________386_____________________________________________________ 

           ___________________________________________________________________                                                      
 2uwn(A) : PRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQPTCI                                                      
         :                                                                                                                          
 2w80(A) : PRCI***************************************************************                                                      
           ___________________________________________________________________                                                      

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		17.9
Translation
(A) 		-0.2
Closure
(%) 		22.4
Bending Residues
( green ) 		  386 - 387
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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