DynDom - Protein Domain Motions

Succinyl-Coa:3-Ketoacid-Coenzyme A Transferase 1, Mitochondrial

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Succinyl-Coa:3-Ketoacid-Coenzyme A Transferase 1, Mitochondrial
Conformer 1 (PDB)	3k6m (C)
Conformer 2 (PDB)	1ooy (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	336	0.99	3 - 261 277 - 279 288 - 356 374 - 396
2	122	0.61	262 - 276 280 - 287 357 - 373 397 - 478

Sequence

`________________________________________________________________________________________________________________________` `3k6m(C) : TKFYTDAVEAVKDIPNGATVLVGGFGLCGIPENLIGALLKTGVKELTAVSNNAGVDNFGLGLLLQSKQIKRMISSYVGENAEFERQYLAGELEVELTPQGTLAERIRAGGAGVPAFYTST` `:` `1ooy(A) : TKFYTDAVEAVKDIPNGATVLVGGFGLCGIPENLIGALLKTGVKELTAVSNNAGVDNFGLGLLLQSKQIKRMISSYVGENAEFERQYLAGELEVELTPQGTLAERIRAGGAGVPAFYTST` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `3k6m(C) : GYGTLVQEGGSPIKYNKDGSIAIASKPREVREFNGQHFILEEAIRGDFALVKAWKADQAGNVTFRKSARNFNLPMCKAAETTVVEVEEIVDIGSFAPEDIHIPKIYVHRLVKGEKYEKRI` `:` `1ooy(A) : GYGTLVQEGGSPIKYNKDGSIAIASKPREVREFNGQHFILEEAIRGDFALVKAWKADQAGNVTFRKSARNFNLPMCKAAETTVVEVEEIVDIGSFAPEDIHIPKIYVHRLVKGEKYEKRI` `________________________________________________________________________________________________________________________` `261________________276________287__________________________________________________________________356_____________372__` `3k6m(C) : ERLSVRnVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNMTVHLQSENGILGLGPYPLQNEVDADLINAGKETVTVLPGASYFSSDESFAMIRGGHVNLTMLGAMQVSKYGDLANW` `:` `1ooy(A) : ER----nVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNMTVHLQSENGILGLGPYPLQNEVDADLINAGKETVTVLPGASYFSSDESFAMIRGGHVNLTMLGAMQVSKYGDLANW` `261________________276________287__________________________________________________________________356_____________372__` `___________________396_____________________________________________________________________________________` `3k6m(C) : MIPGKLVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDRKKGLTLIELWEGLTVDDIKKSTGCDFAVSPKLIPMQQVT*` `:` `1ooy(A) : MIPGKLVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDRKKGLTLIELWEGLTVDDIKKSTGCDFAVSPKLIPMQQVTT` `___________________396_____________________________________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	14.8
Translation (A)	0.8
Closure (%)	91.1
Bending Residues ( green )	261 - 267 276 - 277 279 - 280 287 - 297 356 - 357 372 - 374 396 - 397
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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