Methylenetetrahydrofolate Dehydrogenase- Methenyltetrahydrofolate Cyclohydrolase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Methylenetetrahydrofolate Dehydrogenase- Methenyltetrahydrofolate Cyclohydrolase
  Conformer 1
(PDB) 		2c2x (B)
  Conformer 2
(PDB) 		2c2x (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 149 0.45   4 - 7   119 - 263
2 127 0.44   8 - 118   264 - 279

Sequence


           ____6_____________________________________________________________________________________________________________118___ 
 2c2x(B) : GAIMLDGKATRDEIFGDLKQRVAALDAAGRTPGLGTILVGDDPGSQAYVRGKHADCAKVGITSIRRDLPADISTATLNETIDELNANPDCTGYIVQLPLPKHLDENAALERVDPAKDADG 
         :                                                                                                                          
 2c2x(A) : GAIMLDGKATRDEIFGDLKQRVAALDAAGRTPGLGTILVGDDPGSQAYVRGKHADCAKVGITSIRRDLPADISTATLNETIDELNANPDCTGYIVQLPLPKHLDENAALERVDPAKDADG 
           ____6_____________________________________________________________________________________________________________118___ 

           ________________________________________________________________________________________________________________________ 
 2c2x(B) : LHPTNLGRLVLGTPAPLPCTPRGIVHLLRRYDISIAGAHVVVIGRGVTVGRPLGLLLTRRSENATVTLCHTGTRDLPALTRQADIVVAAVGVAHLLTADMVRPGAAVIDVGVSRTDDGLV 
         :                                                                                                                          
 2c2x(A) : LHPTNLGRLVLGTPAPLPCTPRGIVHLLRRYDISIAGAHVVVIGRGVTVGRPLGLLLTRRSENATVTLCHTGTRDLPALTRQADIVVAAVGVAHLLTADMVRPGAAVIDVGVSRTDDGLV 
           ________________________________________________________________________________________________________________________ 

           _____________257________________________                                                                                 
 2c2x(B) : GDVHPDVWELAGHVSPNPGGVGPLTRAFLLTNVVELAERR                                                                                 
         :                                                                                                                          
 2c2x(A) : GDVHPDVWELAGHVSPNPGGVGPLTRAFLLTNVVELAERR                                                                                 
           _____________257________________________                                                                                 

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		7.9
Translation
(A) 		0.1
Closure
(%) 		8.1
Bending Residues
( green ) 		  6 - 9
  118 - 119
  257 - 264
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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