Myosin Heavy Chain, Cardiac Muscle Beta Isoform

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Myosin Heavy Chain, Cardiac Muscle Beta Isoform
  Conformer 1
(PDB)
2fxm (A)
  Conformer 2
(PDB)
2fxo (D)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 72 0.74   890 - 961
2 42 0.82   848 - 889

Sequence


           __________________________________________________889___________________________________________________________________ 
 2fxm(A) : *PLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 
         :                                                                                                                          
 2fxo(D) : SPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNKRLEDEEEMNAELTAKKRKLEDECSELKRDIDD 
           __________________________________________________889___________________________________________________________________ 

           _______                                                                                                                  
 2fxm(A) : LELTLAK                                                                                                                  
         :                                                                                                                          
 2fxo(D) : LELTLAK                                                                                                                  
           _______                                                                                                                  

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
13.1
Translation
(A)
0.3
Closure
(%)
7.9
Bending Residues
( green )
  889 - 890
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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