Nicotinamide Phosphoribosyltransferase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Nicotinamide Phosphoribosyltransferase
  Conformer 1
(PDB) 		2g95 (B)
  Conformer 2
(PDB) 		2h3b (A)
  Window Length 11
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 377 1.04   14 - 243   310 - 478
2 66 0.57   244 - 309

Sequence


           ________________________________________________________________________________________________________________________ 
 2g95(B) : EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKyEETVFYGLQYILNKYLKGKVVTKEKIQEAKEVYREHFQDDVFNERGWNYILEKYDGHLPIEVKAVPEGSVIPRGNVLFTVENT 
         :                                                                                                                          
 2h3b(A) : EFNIL-aTDSYKVTHYKQYPPNTSKVYSYFECREKkYEETVFYGLQYILNKYLKGKVVTKEKIQEAKEVYREHFQDDVFNERGWNYILEKYDGHLPIEVKAVPEGSVIPRGNVLFTVENT 
           ________________________________________________________________________________________________________________________ 

           ______________________________________________________________________________________________________242_______________ 
 2g95(B) : DPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDH 
         :                                                                                                                          
 2h3b(A) : DPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYL-eTSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDH 
           ______________________________________________________________________________________________________242_______________ 

           _________________________________________________309____________________________________________________________________ 
 2g95(B) : EKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTEAPLIIRPDSGNPLDTVLKVLDILGKKFPVSENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKKWSIEN 
         :                                                                                                                          
 2h3b(A) : EKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTEAPLIIRPDSGNP-dTVLKVLDILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEG-kQKKWSIEN 
           _________________________________________________309____________________________________________________________________ 

           ____________________________________________________________________________________________________________             
 2g95(B) : VSFGSGGALLQKLTRDLLNCSFKCSYVVTNGLGVN--------pNKRSKKGRLSLHRTPAGTFVTLEEGKGDLEEYGHDLLHTVFKNGKVTKSYSFDEVRKNAQLNME             
         :                                                                                                                          
 2h3b(A) : VSFGSGGALLQKLTRDLLNCSFKCSYVVTNGLGVNVFKDPVADPNKRSKKGRLS-hRTPAGNFVTLEEGKGDLEEYGHDLLHTVFKNGKVTKSYSFDEVRKNAQLN**             
           ____________________________________________________________________________________________________________             

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		10.5
Translation
(A) 		0.1
Closure
(%) 		89.4
Bending Residues
( green ) 		  242 - 247
  309 - 319
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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