DynDom - Protein Domain Motions

Perfringolysin O

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Perfringolysin O
Conformer 1 (PDB)	1pfo
Conformer 2 (PDB)	1m3i (B)
Window Length	9
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	235	0.94	56 - 56 58 - 86 184 - 184 186 - 188 192 - 195 205 - 221 224 - 227 277 - 280 284 - 317 320 - 320 322 - 335 339 - 342 378 - 496
2	222	0.72	40 - 55 57 - 57 87 - 183 185 - 185 189 - 191 196 - 204 222 - 223 228 - 276 281 - 283 318 - 319 321 - 321 336 - 338 343 - 377

Sequence

`___________________50__________________________________86_______________________________________________________________` `1pfo : DITDKNQSIDSGISSLSYNRNEVLASNGDKIESFVPKEGKKAGNKFIVVERQKRSLTTSPVDISIIDSVNDRTYPGALQLADKALVENRPTILMVKRKPININIDLPGLKGENSIKVDDP` `:` `1m3i(B) : ******QSIDSGISSLSYNRNEVLASNGDKIESFVPKEGKKAGNKFIVVERQKRSLTTSPVDISIIDSVNDRTYPGALQLADKALVENRPTILMVKRKPININIDLPGLKGENSIKVDDP` `___________________50__________________________________86_______________________________________________________________` `_______________________________183__188____195_199___________________221___227__________________________________________` `1pfo : TYGKVSGAIDELVSKWNEKYSSTHTLPARTQYSESMVYSKSQISSALNVNAKVLENSLGVDFNAVANNEKKVMILAYKQIFYTVSADLPKNPSDLFDDSVTFNDLKQKGVSNEAPPLMVS` `:` `1m3i(B) : TYGKVSGAIDELVSKWNEKYSSTHTLPARTQYSESMVYSKSQISSALNVNAKVLENSLGVDFNAVANNEKKVMILAYKQIFYTVSADLPKNPSDLFDDSVTFNDLKQKGVSNEAPPLMVS` `_______________________________183__188____195_199___________________221___227__________________________________________` `____276_280__________________________________317__________________338_342________________________________377____________` `1pfo : NVAYGRTIYVKLETTSSSKDVQAAFKALIKNTDIKNSQQYKDIYENSSFTAVVLGGDAQEHNKVVTKDFDEIRKVIKDNATFSTKNPAYPISYTSVFLKDNSVAAVHNKTDYIETTSTEY` `:` `1m3i(B) : NVAYGRTIYVKLETTSSSKDVQAAFKALIKNTDIKNSQQYKDIYENSSFTAVVLGGDAQEHNKVVTKDFDEIRKVIKDNATFSTKNPAYPISYTSVFLKDNSVAAVHNKTDYIETTSTEY` `____276_280__________________________________317__________________338_342________________________________377____________` `_______________________________________________________________________________________________________________` `1pfo : SKGKINLDHSGAYVAQFEVAWDEVSYDKEGNEVLTHKTWDGNYQDKTAHYSTVIPLEANARNIRIKARECTGLAWEWWRDVISEYDVPLTNNINVSIWGTTLYPGSSITYN` `:` `1m3i(B) : SKGKINLDHSGAYVAQFEVAWDEVSYDKEGNEVLTHKTWDGNYQDKTAHYSTVIPLEANARNIRIKARECTGLAWEWWRDVISEYDVPLTNNINVSIWGTTLYPGSSITYN` `_______________________________________________________________________________________________________________`

Morph

Morph animation in progress.
Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	7.5
Translation (A)	0.0
Closure (%)	17.4
Bending Residues ( green )	50 - 61 86 - 87 183 - 186 188 - 189 191 - 192 195 - 196 199 - 205 221 - 224 227 - 228 276 - 277 280 - 281 283 - 284 317 - 336 338 - 339 342 - 343 377 - 378
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

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