DynDom - Protein Domain Motions

Regulator Of Nonsense Transcripts 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Regulator Of Nonsense Transcripts 1
Conformer 1 (PDB)	2gjk (A)
Conformer 2 (PDB)	2gk7 (A)
Window Length	11
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	345	1.06	300 - 345 352 - 355 358 - 360 389 - 393 396 - 413 417 - 696
2	241	0.81	346 - 351 356 - 357 361 - 388 394 - 395 414 - 416 697 - 903

Sequence

`____________________________________________________345___351______360_________________________388__393_________________` `2gjk(A) : PLGSRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNFQ` `:` `2gk7(A) : ****RYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLG--kKRIAYFTLPKTDSDMRLMQGDEICLRY-------wKGIGHVIKVPDNYGDEIAIELRSSVG-----tHNFQ` `____________________________________________________345___351______360_________________________388__393_________________` `413_____________________________________________________________________________________________________________________` `2gjk(A) : VDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQL` `:` `2gk7(A) : VDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQL` `413_____________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2gjk(A) : TEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDEsSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA` `:` `2gk7(A) : TEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDEsSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGA` `________________________________________________________________________________________________________________________` `_______________________________________696______________________________________________________________________________` `2gjk(A) : KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVE` `:` `2gk7(A) : KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVE` `_______________________________________696______________________________________________________________________________` `________________________________________________________________________________________________________________________` `2gjk(A) : KITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKE` `:` `2gk7(A) : KITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKE` `________________________________________________________________________________________________________________________` `______________` `2gjk(A) : QKVLVEGPLNNLRE` `:` `2gk7(A) : QKVLVEGPLNNLRE` `______________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.

play backwards

pause

play forwards

Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	8.1
Translation (A)	0.2
Closure (%)	97.7
Bending Residues ( green )	345 - 346 351 - 352 354 - 358 360 - 361 388 - 389 393 - 396 413 - 414 416 - 417 696 - 701
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

Download and extract PyMOL PML script file

Download