Tgf-Beta Receptor Type I

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Tgf-Beta Receptor Type I
  Conformer 1
(PDB) 		1vjy (A)
  Conformer 2
(PDB) 		1b6c (H)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 259 1.08   205 - 231   250 - 253   255 - 265   278 - 498
2 31 1.39   232 - 249   254 - 254   266 - 277

Sequence


           __________________________________________________227___________________249_____________265_________277_________________ 
 1vjy(A) : **************************IARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNR 
         :                                                                                                                          
 1b6c(H) : TTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNR 
           __________________________________________________227___________________249_____________265_________277_________________ 

           ________________________________________________________________________________________________________________________ 
 1vjy(A) : YTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDI----rVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARR 
         :                                                                                                                          
 1b6c(H) : YTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARR 
           ________________________________________________________________________________________________________________________ 

           _________________________________________________________________________________________                                
 1vjy(A) : CSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM                                
         :                                                                                                                          
 1b6c(H) : CSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEG***                                
           _________________________________________________________________________________________                                

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		19.6
Translation
(A) 		0.2
Closure
(%) 		84.5
Bending Residues
( green ) 		  227 - 232
  249 - 250
  252 - 255
  265 - 266
  277 - 278
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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