Thyroid Hormone Receptor Beta-1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Thyroid Hormone Receptor Beta-1
  Conformer 1
(PDB) 		1q4x (A)
  Conformer 2
(PDB) 		1n46 (A)
  Window Length 15
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 200 1.21   218 - 433   454 - 454
2 20 1.0   434 - 453

Sequence


           ________________________________________________________________________________________________________________________ 
 1q4x(A) : GHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLP--------------gKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETL 
         :                                                                                                                          
 1n46(A) : **KPEPTDEEWELIKTVTEAHVATNAQ---wKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETL 
           ________________________________________________________________________________________________________________________ 

           ______________________________________________________________________________________________________433_______________ 
 1q4x(A) : TLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPT 
         :                                                                                                                          
 1n46(A) : TLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPT 
           ______________________________________________________________________________________________________433_______________ 

           __453________                                                                                                            
 1q4x(A) : ELFPPLFLEVFED                                                                                                            
         :                                                                                                                          
 1n46(A) : ELFPPLFLEVFED                                                                                                            
           __453________                                                                                                            

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		20.6
Translation
(A) 		1.1
Closure
(%) 		83.2
Bending Residues
( green ) 		  433 - 434
  453 - 454
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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