Tyrosyl-Trna Synthetase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Tyrosyl-Trna Synthetase
  Conformer 1
(PDB) 		2ag6 (A)
  Conformer 2
(PDB) 		1u7d (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 222 0.87   4 - 109   164 - 169   171 - 171   190 - 304
2 52 0.87   110 - 157   170 - 170   172 - 189

Sequence


           __________________________________________________________________________________________________________109___________ 
 2ag6(A) : MDEFEMIKRNTSEIISEEELREVLKKDEKSALIGFEPSGKIHLGHYLQIKKMIDLQNAGFDIIILLADLHAYLNQKGELDEIRKIGDYNKKVFEAMGLKAKYVYGSSFQLDKDYTLNVYR 
         :                                                                                                                          
 1u7d(B) : *DEFEMIKRNTSEIISEEELREVLKKDEKSAYIGFEPSGKIHLGHYLQIKKMIDLQNAGFDIIILLADLHAYLNQKGELDEIRKIGDYNKKVFEAMGLKAKYVYGSEFQLDKDYTLNVYR 
           __________________________________________________________________________________________________________109___________ 

           _________________________________156__________169_________________189___________________________________________________ 
 2ag6(A) : LALKTTLKRARRSMELIAREDENPKVAEVIYPIMQVNPLHYEGVDVAVGGMEQRKIHMLARELLPKKVVCIHNPVLTGLDGEGKMSSSKGNFIAVDDSPEEIRAKIKKAYCPAGVVEGNP 
         :                                                                                                                          
 1u7d(B) : LALKTTLKRAR------------pKVAEVIYPIMQVNDIHYLGVDVAVGGME---iHMLARELLPKKVVCIHNPVLTGLDGEG------gNFIAVDDSPEEIRAKIKKAYCPAGVVEGNP 
           _________________________________156__________169_________________189___________________________________________________ 

           ___________________________________________________________________                                                      
 2ag6(A) : IMEIAKYFLEYPLTIKRPEKFGGDLTVNSYEELESLFKNKELHPMDLKNAVAEELIKILEPIRKRLL                                                      
         :                                                                                                                          
 1u7d(B) : IMEIAKYFLEYPLTIKRPEKFGGDLTVNSYEELESLFKNKELHPMDLKNAVAEELIKILEPIRKRL*                                                      
           ___________________________________________________________________                                                      

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		11.8
Translation
(A) 		0.3
Closure
(%) 		27.4
Bending Residues
( green ) 		  109 - 110
  156 - 165
  169 - 172
  189 - 190
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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