Urokinase Plasminogen Activator Surface Receptor

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Urokinase Plasminogen Activator Surface Receptor
  Conformer 1
(PDB) 		1ywh (A)
  Conformer 2
(PDB) 		2fd6 (U)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 134 2.08   3 - 103   107 - 108   110 - 127   144 - 156   168 - 181
2 110 1.48   104 - 106   109 - 109   128 - 143   157 - 167   182 - 273

Sequence


           _______________________________________________________________________________________________103_____________________1 
 1ywh(A) : *LRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGrSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDV 
         :                                                                                                                          
 2fd6(U) : SLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEe---LELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGN-----yLECISCGSSDMSCERGRHQSLQCRSPEEQCLDV 
           _______________________________________________________________________________________________103_____________________1 

           27_____________________156________167___________181_____________________________________________________________________ 
 1ywh(A) : VTHWIQrPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGQSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHA 
         :                                                                                                                          
 2fd6(U) : VTHW-----dDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQ-- 
           27_____________________156________167___________181_____________________________________________________________________ 

           _____________________________                                                                                            
 1ywh(A) : HLGDAFSMNHIDVSCCTKSGCNHPDLDVQ                                                                                            
         :                                                                                                                          
 2fd6(U) : -lGDAFSMNHIDVSCCTKSGCNHPD****                                                                                            
           _____________________________                                                                                            

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		26.1
Translation
(A) 		-0.1
Closure
(%) 		24.7
Bending Residues
( green ) 		  103 - 112
  127 - 128
  140 - 144
  156 - 157
  167 - 168
  181 - 182
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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